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Dna Damage And Repair

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DNA Damage DNA Repair and Disease

DNA Damage  DNA Repair and Disease Book
Author : Miral Dizdaroglu,R Stephen Lloyd
Publisher : Royal Society of Chemistry
Release : 2020-11-19
ISBN : 1839162562
File Size : 28,6 Mb
Language : En, Es, Fr and De

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Book Summary :

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

DNA Damage and Repair

DNA Damage and Repair Book
Author : A. Castellani
Publisher : Springer Science & Business Media
Release : 2013-03-09
ISBN : 1475750161
File Size : 28,8 Mb
Language : En, Es, Fr and De

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Book Summary :

The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have their own interna tional meetings and although the meetings often have sessions devoted to DNA repair, they do not bring together a wide diversity of international workers in the field to exchange ideas. The purpose of the Congress was to facilitate such an exchange among scientists representing many fields of endeavor and many countries. The 37 manuscripts in this volume, presented by the invited spea kers during the four and half days of the Congress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en dogenous oxidative damages. The Congress and its Proceedings are dedicated to two international leaders in the field of DNA damage and repair, Alexander Hollaender of the United States and Adriano Buzzati Traverso of Italy. Hollaender, who died in December 1986, was one of the first investigators to recognize the damage to DNA was important in cell killing and mutagenesis. His early work indicated that cells could recover from radiation injury.

DNA Damage and Repair

DNA Damage and Repair Book
Author : Jac A. Nickoloff,Merl F. Hoekstra
Publisher : Springer Science & Business Media
Release : 1998-08-12
ISBN : 1592594557
File Size : 30,7 Mb
Language : En, Es, Fr and De

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Book Summary :

Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.

DNA Damage DNA Repair and Disease

DNA Damage  DNA Repair and Disease Book
Author : Miral Dizdaroglu,R Stephen Lloyd
Publisher : Royal Society of Chemistry
Release : 2020-11-19
ISBN : 1839160861
File Size : 21,7 Mb
Language : En, Es, Fr and De

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Book Summary :

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

DNA Repair and Mutagenesis

DNA Repair and Mutagenesis Book
Author : Errol C. Friedberg,Graham C. Walker,Wolfram Siede,Richard D. Wood
Publisher : American Society for Microbiology Press
Release : 2005-11-22
ISBN : 1555813194
File Size : 31,5 Mb
Language : En, Es, Fr and De

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Book Summary :

An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

New Research Directions in DNA Repair

New Research Directions in DNA Repair Book
Author : Clark Chen
Publisher : BoD – Books on Demand
Release : 2013-05-22
ISBN : 9535111140
File Size : 29,6 Mb
Language : En, Es, Fr and De

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Book Summary :

This book is intended for students and scientists working in the field of DNA repair. Select topics are presented here to illustrate novel concepts in DNA repair, the cross-talks between DNA repair and other fundamental cellular processes, and clinical translational efforts based on paradigms established in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.

Mechanisms of DNA Damage and Repair

Mechanisms of DNA Damage and Repair Book
Author : Michael G. Simic,Lawrence Grossman,Arthur C. Upton
Publisher : Unknown
Release : 2014-09-01
ISBN : 9781461594635
File Size : 49,9 Mb
Language : En, Es, Fr and De

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Book Summary :

Download Mechanisms of DNA Damage and Repair book written by Michael G. Simic,Lawrence Grossman,Arthur C. Upton and published by with total hardcover pages 596 . Available in PDF, EPUB, and Kindle, read book directly with any devices anywhere and anytime.

DNA Repair and Cancer

DNA Repair and Cancer Book
Author : Srinivasan Madhusudan,David M. Wilson III
Publisher : CRC Press
Release : 2013-01-22
ISBN : 1466577444
File Size : 23,5 Mb
Language : En, Es, Fr and De

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Book Summary :

DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.